AnelleO Products

Product Platform for Women’s Health Needs

In Development

  • ANL0102 for Infertility

Anelleo - Infertility

The Problem

Infertility remains one of the major unmet medical needs globally.

In the United States, infertility affects around 13-15% of reproductive-aged couples, and the number of women treated for infertility per year is around 1.7 million. Assisted reproductive technology (ART) includes all fertility treatments with the main type of ART being in vitro fertilization (IVF). Approximately 2.3% of all infants are born using Assisted Reproductive Technology (ART). As part of ART, supplementation of progesterone (PRO) promotes fertility, prevents miscarriages and even prevents pre-term labor.

Current available options for PRO supplementation are limited to messy vaginal gel (Crinone®) and inserts (Endometrin®) that require administration 2-3 times per day, or painful daily IM injections that require another person’s help to administer and have side effects such as abscess formation.

Infertility in the US

Anelleo: The Solution

The AnelleO Solution

The AnelleO solution offers progesterone supplementation with an intravaginal ring (IVR) system, which delivers progesterone for approximately one month with each ring, thus requiring only 2-3 IVR systems for the entire art period. Utilizing state-of-the-art 3D printing technology, AnelleO has designed and is manufacturing each ANLO102 to:

  • Release progesterone over ~28 days

  • Enhance patient compliance with an efficient and patient friendly treatment

  • Match or exceed efficacy of current technologies for progesterone supplementation in ART.

AnelleO is Initiating IND-enabling studies for ANLO102 in 2025.

In Research

  • Hormone replacement therapy

    Extended duration intravaginal systems to deliver low-dose replacement hormones for postmenopausal women

  • Infectious Diseases

    Short duration intravaginal systems to treat a variety of infections including those that are sexually-transmitted

  • Oncology

    Extended duration Intravaginal systems targeting a variety of gynecological cancers.

AnelleO is harnessing the advancements in the speed and scale of 3D printing technology for novel solutions in Women’s Health. AnelleO’s first products are Intravaginal Rings (IVRs), which offer a unique platform for sustained delivery of therapeutics – a non-invasive, self-administered and retrievable platform that can deliver drugs over a period of days to months.

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